It is America’s fourth-longest Interstate Highway, and the southernmost major interstate highway, running from Santa Monica, California, to Jacksonville, Florida.
Source: whenonearth.net
However, the 150 mile stretch from Phoenix, Arizona to the California border is especially dangerous, accounting for approximately 85 deaths per year. That section has very little in the way of population and is mostly deserted.
2. I-95 in Connecticut
I-95 runs north and south, from Maine (US/Canada border) all the way south into Miami, Florida, though technically sections in Pennsylvania and New Jersey which are still under construction (scheduled completion 2018).
It is the longest (north and south) and one of oldest interstate highways in the US.
Source: city-data.com
Running along the eastern border of the United States it also cuts through the most densely population centers in the nation. I-95 combined, totals 1,919.74 mi (3,090 km), yet the vast majority of accidents happen on an 8 mile stretch in the city of Norwalk.
